IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITIES OF SEED EXTRACT OF SOLANUM VIRGINIANUM

S.GNANAVEL, S.KAVITHA, M.DHINESH KUMAR, K.KANNAN

Abstract


The aim of the present study is to evaluate the antioxidant and anticancer activities of seed extract of Solanum Virginianum. The antioxidant activity was assessed using DPPH scavenging assay while the anticancer property of the Solanum virginanum in swiss albino mice against Dalton Ascites Lymphoma (DAL).Tumor was induced in mice by intraperitoneal inoculation of Dalton Ascites Lymphoma cells (1 x 105 cells / mouse).The seed extract was found to possess significant antioxidant and anticancer activities.

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Baker JT,BorrisRP,Carte B et al.Natural products drug discovery and Department :New perspective internal collaboration.J Nat prod.1995; 58:1325-1357.

Vongtau HO, Abbah J, Chindo BA, Mosugu O, Salawu AO, Kwanashie HO, Gamaliel KS: Central inhibitory effects of the methanol extract of Neorautaneniait's root in rats and mice. J Pharm Biol 2005, 43:113– 120.

Oluyemi KA, Okwuonu UC, Baxter DG, Oyesola TO: Toxic effects of

Methanolicextract of Aspiliaafricana leaf on the estrous cycle and uterine tissues of Wistar rats. Int J Morphol 2007, 25:609–614.

Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. Oxford University Press, Oxford, UK. 2003.

Edris AE. Pharmaceutical and therapeutic potential oils and their individual volatile constituents.A review. Phototherapy Research.2007; 21:308-323.

Espin JC, Garcia-Conesa MT and Tomas Barberan FA. Nutraceutical facts and fiction.Phytochemistry.2007; 68(24):2986-3008.

CraggG.M,NewmanDJ.Plants as a source of anticancer agents .J.Ethnopharmacol.2005;100:72-79

L.Borgato, F.Pisani,A.Furini. Plant regeneration from leaf protoplasts of Solanumvirginianum L.(Solanaceae) Plant Cell Tiss Organ Cult(2007) 88: 247-252.

Sandra knapp.F.L.S and Charles E.Jarvis.F.L.S.The typification of the names of new world Solanum species described by Linnaeus. Botanical Journal of the LinneanSocieg(1990),104: 325- 367.

Trease GE, Evans WC.Text book of Pharmacognosy.13th ed.London:Balliere Tindal; 1989,p.176-180.

SofoworaA.Medicinal plants and traditional medicine in Africa Ibadan: Spectrum Books; 1993, p.150.

M.R Saha, S.M.RHasan,R.Akter,M.MHossain,MA.Alam and M.E.H Mazumder, Invitro free radical scavenging activity of methanolic extract of the leaves Mimusopselengilinn,Bangl.J.Vet.Med 2008:6(2),197-202.

Arihara Siva Kumar G et.al.Effect of methanolic extract of adenantherapavonina on Dalton ascetic lymphoma.Indian Journal of pharmacy and Biotechnology ISSN: 2320 – 3471 p-138-141.

Jaya Kumar D, Jhancy Mary S, JayashanthiR.Antioxidant and antimicrobial activities of Wedilatrilobata and morindapubescences.Asian J.Chem 2011; 1:305-308.

Chidambra Murthy KN,Vanitha A, Mahadeva Swamy M,Ravishankar GA, Antioxidant and Antimicrobial activity of Cissusquadrangularis L.Journal of Medicinal Food 2003; 6(2): 99-105.


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