NARDOSTACHYS JATAMANSI DC. POTENTIAL HERB WITH CNS EFFECTS

Abstract

Nardostachys jatamansi is classified as hypno-sedative in Ayurveda. It is used in
treatment of insomnia, hysteria and depressive illness. The plant abounds in
sesquiterpenes predominantly; jatamansone and nardostachone. The plant has
demonstrated several pharmacological activities including hepatoprotective, cardio
protective and hypolipidemic and antifungal. The significant effect is on the central
nervous system, as diverse pharmacological actions, ranging from sedative to nootropic
have been reported. Animal and clinical research with jatamansone, the active principle
of the plant, has justified hypno-sedative claim of Ayurveda. The review summarizes,
phytochemical and pharmacological investigations carried out on the plant.