Appendectomized Patient and Infections after Surgery
Appendicitis is one of the common surgeries all over the world, and its diagnosis is difficult and based on clinical
examinations or its symptoms. Moreover, after the surgery is accomplished, it is probable that the patient is faced with
certain problems and complications. In this regard, the present study was carried out in order to review the infections
caused after appendicitis surgery. The databases like PubMed, Google Scholar, and Science Direct and relevant articles
were collected, in which keywords like appendicitis surgery, perforation, laparoscopy, and infection had been used. A total
number of 6,000 articles were retrieved, out of which, 74 relevant articles were examined. The results of the present
study indicated that perforated appendix can be the biggest cause of infection and abscess after intra-abdominal surgery.
An increase in the level of C-reactive protein and leukocytes is accompanied with the risk of postoperative complications
including infection and abscess. Numerous studies have reported that formation of infection and abscess after laparoscopic
appendectomy is a little more than open appendectomy. It is not necessary to consume antibiotics after a non-perforated
appendectomy. It is sufficient to consume antibiotics for 3 to 5 days after a perforated appendectomy to prevent infection
and abscess. With the above results now it is evident that the appendicitis and its complications are still a common problem
among people all over the world. There is still much to discuss among the surgeons with regards to appendicitis and its
Hall MJ, DeFrances CJ, Williams SN, Golosinskiy A,
Schwartzman A. National hospital discharge survey: 2007
summary. Natl Health Stat Report. 2010; 29(29):1–20.
Ingraham AM, Cohen ME, Bilimoria KY, Pritts TA, Ko
CY, Esposito TJ. Comparison of outcomes after laparoscopic
versus open appendectomy for acute appendicitis at
ACS NSQIP hospitals. Surgery. 2010; 148(4):625–37.
Available from: file:///C:/Users/Wafa/Downloads/Telegram
Kapischke M, Friedrich F, Hedderich J, Schulz T, Caliebe A.
Laparoscopic versus open appendectomy—quality of life 7
years after surgery. Langenbeck’s Archives of Surgery. 2011;
Masoomi H, Nguyen NT, Dolich MO, Mills S, Carmichael
JC, Stamos MJ. Laparoscopic appendectomy trends and
outcomes in the United States: data from the Nationwide
Inpatient Sample (NIS), 2004‐2011. The American Surgeon.
Wilson DG, Bond AK, Ladwa N, Sajid MS, Baig MK, Sains
P. Intra-abdominal collections following laparoscopic versus
open appendicectomy: an experience of 516 consecutive
cases at a district general hospital. Surgical Endoscopy.
Bansal S, Banever GT, Karrer FM, Partrick DA. Appendicitis
in children less than 5 years old: influence of age on presentation
and outcome. The American Journal of Surgery.
Alloo J, Gerstle T, Shilyansky J, Ein SH. Appendicitis in
children less than 3 years of age: a 28-year review. Pediatric
Surgery International. 2004; 19(12):777–9.
Kelly KN, Fleming FJ, Aquina CT, Probst CP, Noyes K,
Pegoli W, et al. Disease severity, not operative approach,
drives organ space infection after pediatric appendectomy.
Annals of Surgery. 2014; 260(3):466–73.
Romano A, Parikh P, Byers P, Namias N. Simple acute appendicitis
versus non-perforated gangrenous appendicitis:
is there a difference in the rate of post-operative infectious
complications? Surgical Infections. 2014; 15(5):517–20.
Markar SR, Blackburn S, Cobb R, Karthikesalingam A,
Evans J, Kinross J, et al. Laparoscopic versus open appendectomy
for complicated and uncomplicated appendicitis
in children. Journal of Gastrointestinal Surgery. 2012;
Asarias JR, Schlussel AT, Cafasso DE, Carlson TL, Kasprenski
MC, Washington EN, et al. Incidence of postoperative
intraabdominal abscesses in open versus laparoscopic
appendectomies. Surgical Endoscopy. 2011; 25(8):2678–83.
Fleming FJ, Kim MJ, Messing S, Gunzler D, Salloum R,
Monson JR. Balancing the risk of postoperative surgical infections:
a multivariate analysis of factors associated with
laparoscopic appendectomy from the NSQIP database. Annals
of Surgery. 2010; 252(6):895–900.
Bliss LA, Yang CJ, Kent TS, Ng SC, Critchlow JF, Tseng JF.
Appendicitis in the modern era: universal problem and
variable treatment. Surgical Endoscopy. 2015; 29(7):1897–
Blanco FC, Sandler AD, Nadler EP. Increased incidence of
perforated appendicitis in children with obesity. Clinical
Pediatrics. 2012; 51(10):928–32.
DeUgarte DA, Stark R, Kaji AH, Yaghoubian A, Tolan A,
Lee SL. Obesity does not impact outcomes for appendicitis.
The American Surgeon. 2012; 78(2):254–7.
Garey CL, Laituri CA, Little DC, Ostlie DJ, Peter SDS. Outcomes
of perforated appendicitis in obese and nonobese
children. Journal of Pediatric Surgery. 2011; 46(12):2346–8.
Bratton SL, Haberkern CM, Waldhausen JH. Acute appendicitis
risks of complications: age and Medicaid insurance.
Pediatrics. 2000; 106(1):75–8.
Henry MC, Walker A, Silverman BL, Gollin G, Islam S, Sylvester
K, et al. Risk factors for the development of abdominal
abscess following operation for perforated appendicitis
in children: a multicenter case-control study. Archives of
Surgery. 2007; 142(3):236–41.
Walker A, Hatch Q, Drake T, Nelson DW, Fitzpatrick E,
Bingham J, et al. Predictors of appendiceal perforation in
an equal access system. Journal of Surgical Research. 2014;
Panagiotopoulou I, Parashar D, Lin R, Antonowicz S, Wells
A, Bajwa F, et al. The diagnostic value of white cell count,
C-reactive protein and bilirubin in acute appendicitis and
its complications. The Annals of the Royal College of Surgeons
of England. 2013; 95(3):215–21.
Thereaux J, Veyrie N, Corigliano N, Servajean S, Czernichow
S, Bouillot J-L. Is laparoscopy a safe approach for diffuse
appendicular peritonitis? Feasibility and determination of
risk factors for post-operative intra-abdominal abscess.
Surgical Endoscopy. 2014; 28(6):1908–13.
Brenner DJ, Hall EJ. Computed tomography—an increasing
source of radiation exposure. N Engl J Med. 2007;
23. Papandria D, Goldstein SD, Rhee D, Salazar JH, Arlikar
J, Gorgy A, et al. Risk of perforation increases with delay in
recognition and surgery for acute appendicitis. Journal of
Surgical Research. 2013; 184(2):723–9.
Teixeira PG, Sivrikoz E, Inaba K, Talving P, Lam L, Demetriades
D. Appendectomy timing: waiting until the next
morning increases the risk of surgical site infections. Annals
of Surgery. 2012; 256(3):538–43.
Drake FT, Mottey NE, Farrokhi ET, Florence MG, Johnson
MG, Mock C, et al. Time to appendectomy and risk
of perforation in acute appendicitis. JAMA Surgery. 2014;
Bhangu A. United Kingdom National Surgical Research
Collaborative. Safety of short, in-hospital delays before
surgery for acute appendicitis: multicentre cohort study,
systematic review, and meta-analysis. Ann Surg. 2014;
McBurney C. The incision made in the abdominal wall in
cases of appendicitis, with a description of a new method of
operating. Annals of Surgery. 1894; 20(1):38.
Semm K. Endoscopic appendectomy. Endoscopy. 1983;
Golub R, Siddiqui F, Pohl D. Laparoscopic versus open appendectomy:
a metaanalysis. Journal of the American College
of Surgeons. 1998; 186(5):545–53.
Bennett J, Boddy A, Rhodes M. Choice of approach for appendicectomy:
a meta-analysis of open versus laparoscopic
appendicectomy. Surgical Laparoscopy Endoscopy and
Percutaneous Techniques. 2007; 17(4):245–55.
Andersen BR, Kallehave FL, Andersen HK. Antibiotics versus
placebo for prevention of postoperative infection after
appendicectomy. Cochrane Database Syst Rev. 2005; 3.
Coakley BA, Sussman ES, Wolfson TS, Bhagavath AS, Choi
JJ, Ranasinghe NE, et al. Postoperative antibiotics correlate
with worse outcomes after appendectomy for nonperforated
appendicitis. Journal of the American College of Surgeons.
Nadler EP, Gaines BA. The Surgical Infection Society guidelines
on antimicrobial therapy for children with appendicitis.
Surgical Infections. 2008; 9(1):75–83.
Daskalakis K, Juhlin C, Påhlman L. The use of pre-or
postoperative antibiotics in surgery for appendicitis: a
systematic review. Scandinavian Journal of Surgery. 2014;
Solomkin JS. Evaluating evidence and grading recommendations:
the SIS/IDSA guidelines for the treatment of complicated
intra-abdominal infections. Surgical Infections.
van Rossem CC, Schreinemacher MH, Treskes K, et al.
Duration of antibiotic treatment after appendicectomy
for acute complicated appendicitis. Br J Surg. 2014;
Clark JJ, Johnson SM. Laparoscopic drainage of intraabdominal
abscess after appendectomy: an alternative to laparotomy
in cases not amenable to percutaneous drainage. J
Pediatr Surg. 2011; 46(7):1385–9.
Scarborough JE, Bennett KM, Pappas TN. Racial disparities
in outcomes after appendectomy for acute appendicitis.
Am J Surg. 2012; 204(1):11–7.
- There are currently no refbacks.
Listed as Green Publisher